Phthalate and phthalate replacement concentrations in relationship to adiposity in a multi-racial cohort of children.

ABSTRACT:

Background/objective

Phthalates and phthalate replacements are used in multiple everyday products, making many of them bioavailable to children. Experimental studies suggest that phthalates and their replacements may be obesogenic, however, epidemiologic studies remain inconsistent. Therefore, our objective was to examine the association between phthalates, phthalate replacements and childhood adiposity/obesity markers in children.

Subjects/methods

A cross-sectional study was conducted in 630 racial/ethnically diverse children ages 4-8 years. Urinary oxidative metabolites of DINCH and DEHTP, three low molecular weight (LMW) phthalates, and eleven high molecular weight (HMW) phthalates were measured. Weight, height, waist circumference and % body fat were measured. Composite

SUBMITTER: Hunt KJ 

PROVIDER: S-EPMC11347365 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature