Resting-state functional connectivity of the occipital cortex in different subtypes of Parkinson's disease.

ABSTRACT:

Aims

To examine whether functional connectivity (FC) of the occipital gyrus differs between patients with Parkinson's disease (PD) motor subtypes and healthy controls (HCs).

Methods

We enrolled 30 PD patients exhibiting tremor dominance (TD), 43 PD patients with postural instability and gait disturbance (PIGD), and 42 HCs. The occipital gyrus was partitioned into six areas of interest, as seed points, via the Anatomical Automatic Labeling template to compare the FC of the three groups and analyze the relationship of FC with clinical scales.

Results

Compared with the PIGD group, the TD group showed increased FC between the left superior occipital gyrus (SOG.L) and right median cingulate and paracingulate gyri (DCG.R)/right paracentral lobule/bilateral inferior parietal

SUBMITTER: Lan Y 

PROVIDER: S-EPMC11347390 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature