Effect of hypoglycemic events on cognitive function in individuals with type 2 diabetes mellitus: a dose-response meta-analysis.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) is widely acknowledged as a vital warning sign contributing to cognitive dysfunction. However, there is still a lack of consensus on whether hypoglycemic events resulting from poor glycemic control increase the risk of cognitive dysfunction in people with diabetes, and the potential dose-response correlation between hypoglycemic events and cognitive dysfunction remains unexplored. The primary objective of the current study was to assess the contribution of hypoglycemic events to cognitive dysfunction in T2DM patients and the dose-response correlation between the two.

Methods

A comprehensive search of nine major databases was executed from inception to May 2023. We screened all observational studies examining the connection between h

SUBMITTER: Ye M 

PROVIDER: S-EPMC11347434 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature