Under-representation of older Indian persons with cancer in clinical trials.

ABSTRACT:

Objective

Older patients with cancer have traditionally been under-represented in global clinical trials. There are no data from India regarding this issue.

Methods and analysis

This was a retrospective analysis done at our institute on interventional studies conducted between 2003 and 2023 in adult patients with malignancies. We excluded studies done exclusively in the paediatric population and observational studies.

Results

We included 21 894 patients enrolled in 150 interventional trials from the departments of surgical, medical, and radiation oncology, anaesthesia, and clinical pharmacology; 110 (73.3%) were investigator initiated. There were 38 trials (25.3%) in breast cancer (6141 patients, 28%), and 33 (22%) in head and neck cancer (6975 patients, 31.9%). Studi

SUBMITTER: Noronha V 

PROVIDER: S-EPMC11347695 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature