Association between acetaminophen administration and outcomes in critically ill patients with gout and hypertension.

ABSTRACT:

Background

Acetaminophen is a commonly used medication, yet its recommendation for patients with comorbid conditions of gout and hypertension is contradictory, and the impact of its usage on clinical outcomes in real-world practical settings remains uncertain. The aim of this study was to investigate the association between acetaminophen administration and clinical outcomes in critically ill patients with gout and hypertension, utilizing real-world data.

Methods

A retrospective cohort study was conducted based on the MIMIC-IV (Medical Information Mart in Intensive Care-IV) database. Adult critically ill patients with gout and hypertension were included in the analysis. The exposure was acetaminophen use during ICU stay. The primary outcome was in-hospital mortality. The seco

SUBMITTER: Yi XQ 

PROVIDER: S-EPMC11348437 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature