The association between ibuprofen administration in children and the risk of developing or exacerbating asthma: a systematic review and meta-analysis.

ABSTRACT:

Background

Ibuprofen is one of the most commonly used analgesic and antipyretic drugs in children. However, its potential causal role in childhood asthma pathogenesis remains uncertain. In this systematic review, we assessed the association between ibuprofen administration in children and the risk of developing or exacerbating asthma.

Methods

We searched MEDLINE, Embase, Cochrane Library, CINAHL, Web of Science, and Scopus from inception to May 2022, with no language limits; searched relevant reviews; and performed citation searching. We included studies of any design that were primary empirical peer-reviewed publications, where ibuprofen use in children 0-18 years was reported. Screening was performed in duplicate by blinded review. In total, 24 studies met our criteria. Da

SUBMITTER: Baxter L 

PROVIDER: S-EPMC11348613 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature