Association of thyroid autoantibodies with aggressive characteristics of papillary thyroid cancer: a case-control study.

ABSTRACT:

Purpose

Although the potential association between autoimmune thyroiditis and papillary thyroid cancer (PTC) has been acknowledged, whether the clinicopathological features of PTC will be affected by thyroid autoantibodies remains unknown.

Patients and methods

We conducted a case-control study to investigate the association of thyroid autoantibodies with clinicopathological characteristics of PTC in 15,305 patients (including 11,465 females and 3,840 males) from 3 medical centers in the central province of China. Logistic regression and restricted cubic spline models were performed to analyze the association of thyroid autoantibodies with clinicopathological features of PTC.

Results

In total, out of the 15,305 patients enrolled in this study, 10,087 (65.9%) had negati

SUBMITTER: Tan HL 

PROVIDER: S-EPMC11348733 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature