Multimodal treatment according to the NPC-GPOH trials in adult patients with nasopharyngeal cancer-Analysis based on a single-center experience.

ABSTRACT:

Background and aim

The German NPC-GPOH trials introduced treatment including neoadjuvant chemotherapy, radiochemotherapy (RCT) and antiviral treatment in patients aged 25 years or younger with nasopharyngeal cancer (NPC). We conducted a retrospective study on outcomes of patients at the age of ≥26 years treated accordingly at our institution.

Methods

Consecutive patients who received primary RCT for NPC were included. The Kaplan-Meier method was used to calculate survival probabilities, and the Cox regression analysis was used to test for an influence of the variables on outcomes. Acute and late toxicity were evaluated via CTCAE criteria and LENT/SOMA criteria, respectively.

Results

In total, 30 patients were included. Diagnosis was made from 09/1994 to 11/2016. The m

SUBMITTER: Leu M 

PROVIDER: S-EPMC11349452 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature