Harnessing nature's pharmacy: investigating natural compounds as novel therapeutics for ulcerative colitis.

ABSTRACT:

Backgrounds

Ulcerative colitis (UC) is a form of chronic inflammatory bowel disease, and UC diagnosis rates continue to rise throughout the globe. The research and development of new drugs for the treatment of UC are urgent, and natural compounds are an important source. However, there is a lack of systematic summarization of natural compounds and their mechanisms for the treatment of UC.

Methods

We reviewed the literature in the databases below from their inception until July 2023: Web of Science, PubMed, China National Knowledge Infrastructure, and Wanfang Data, to obtain information on the relationship between natural compounds and UC.

Results

The results showed that 279 natural compounds treat UC through four main mechanisms, including regulating gut microbiota an

SUBMITTER: Huang Y 

PROVIDER: S-EPMC11349575 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature