Pneumococcal carriage and serotype distribution in children with nephrotic syndrome.

ABSTRACT:

Background

Patients with nephrotic syndrome (NS) are at a higher risk of developing invasive pneumococcal disease (IPD). Pneumococcal carriage studies are helpful tools for detecting potentially infectious serotypes and guiding immunization efforts. Pneumococcal nasopharyngeal colonization is common, and IPD can easily occur in an immunosuppressed state. Limited information is available regarding the frequency of pneumococcal carriage in individuals with NS. The aim of this study was to evaluate pneumococcal carriage and serotype distribution in children with NS.

Methods

Pneumococcal carriage was detected by real-time PCR assays from nasopharyngeal swab samples from 98 children with NS, and 100 healthy controls. Isolates were serotyped by real-time PCR.

Results

The pn

SUBMITTER: Erem T 

PROVIDER: S-EPMC11349834 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature