Clinical recognition of frontotemporal dementia with right anterior temporal predominance: A multicenter retrospective cohort study.

ABSTRACT:

Introduction

Although frontotemporal dementia (FTD) with right anterior temporal lobe (RATL) predominance has been recognized, a uniform description of the syndrome is still missing. This multicenter study aims to establish a cohesive clinical phenotype.

Methods

Retrospective clinical data from 18 centers across 12 countries yielded 360 FTD patients with predominant RATL atrophy through initial neuroimaging assessments.

Results

Common symptoms included mental rigidity/preoccupations (78%), disinhibition/socially inappropriate behavior (74%), naming/word-finding difficulties (70%), memory deficits (67%), apathy (65%), loss of empathy (65%), and face-recognition deficits (60%). Real-life examples unveiled impairments regarding landmarks, smells, sounds, tastes, and bodi

SUBMITTER: Ulugut H 

PROVIDER: S-EPMC11350044 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature