Dataset Information

Infection and Genomic Characteristics of Campylobacter jejuni from a Patient Without Diarrhea - China, 2018.

ABSTRACT:

What is already known about this topic?

A 20-month-old boy was admitted to the hospital with a maximum temperature of 40 °C and a single convulsion. Unexpectedly, blood culture detected Francisella tularensis (F. tularensis) using the VITEK 2 Compact System.

What is added by this report?

After incubation of the patient's blood for 48 hours, the cultured strain was identified as Campylobacter jejuni, named L8, excluding F. tularensis. In the genome sequence of L8, we found a novel Type VI Secretion System (T6SS), of which the conserved C-terminal VgrG domain from positions 561 to 884 showed significant changes.

What are the implications for public health practice?

It should be underscored that relying solely on automatic bacterial identification instruments for accurate strain identification is unreliable. Moreover, our study suggests that the potential effect of T6SS should be considered when studying the genetic features of a patient's clinical phenotypes.

SUBMITTER: Yang X

PROVIDER: S-EPMC11350234 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Infection and Genomic Characteristics of <i>Campylobacter jejuni</i> from a Patient Without Diarrhea - China, 2018.

Yang Xiangdong X Wang Wen W Cui Chajin C Yu Binbin B Zhang Qing Q Wang Yanhua Y

China CDC weekly 20240801 33

<h4>What is already known about this topic?</h4>A 20-month-old boy was admitted to the hospital with a maximum temperature of 40 °C and a single convulsion. Unexpectedly, blood culture detected <i>Francisella tularensis</i> (<i>F. tularensis</i>) using the VITEK 2 Compact System.<h4>What is added by this report?</h4>After incubation of the patient's blood for 48 hours, the cultured strain was identified as <i>Campylobacter jejuni</i>, named L8, excluding <i>F. tularensis</i>. In the genome seque ...[more]

PMID: 39211440

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