Exploring the Antimicrobial Resistance Profile of Salmonella typhi and Its Clinical Burden.

ABSTRACT: Background: Typhoid fever caused by Salmonella enterica serovar Typhi (S. typhi) continues to pose a significant risk to public health in developing countries, including Pakistan. This study investigated the epidemiological factors linked to suspected and confirmed S. typhi infections in Peshawar's hospital population. Methodology: A total of 5735 blood samples of patients with suspected enteric fever were collected from September 2022 to November 2023. S. typhi infection was confirmed using microbiological culture of blood samples, biochemical-based tests, and DNA-sequencing methods. Drug sensitivity testing on cultures was conducted as per the CLSI guidelines. Chi-square tests were used to analyze the clinical and epidemiologic characteristics of

SUBMITTER: Asghar M 

PROVIDER: S-EPMC11350866 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature