The Double-Edged Sword of Total Antioxidant Capacity: Clinical Significance and Personal Experience.

ABSTRACT: Oxidative stress (OS) could be a condition underlying several human diseases, despite the physiological role of reactive oxygen species (oxidative eustress). Therefore, antioxidant compounds could represent a modulatory mechanism for maintaining a proper redox balance and redox signaling. When antioxidants are insufficient or overwhelmed, OS ensues, causing multiple damages at molecular, tissue, and cellular levels. This study focuses on the role of total antioxidant capacity (TAC) as a biomarker to be interpreted according to several clinical scenarios. After a brief description of various assay methods to elucidate terminology and physiopathological roles, we focus on the hormonal influence on TAC in blood plasma and other biological fluids, as different endocrine systems can modulate th

SUBMITTER: Silvestrini A 

PROVIDER: S-EPMC11351343 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature