Feasibility of using real-world data to emulate substance use disorder clinical trials: a cross-sectional study.

ABSTRACT:

Introduction

Real-world evidence is receiving considerable attention as a way to evaluate the efficacy and safety of medical products for substance use disorders (SUDs). However, the feasibility of using real-world data (RWD) to emulate clinical trials evaluating treatments for SUDs is uncertain. The aim of this study is to identify the number of clinical trials evaluating treatments for SUDs with reported results that could be feasibly emulated using observational data from contemporary insurance claims and/or electronic health record (EHR) data.

Methods

In this cross-sectional study, all phase 2-4 trials evaluating treatments for SUDs registered on ClinicalTrials.gov with reported results were identified. Each trial was evaluated to determine if the indications, interventi

SUBMITTER: Janda GS 

PROVIDER: S-EPMC11351457 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature