Cytokinin and ALOG proteins regulate pluripotent stem cell identity in the moss Physcomitrium patens.

ABSTRACT: The shoot apical meristem (SAM) contains pluripotent stem cells that produce all the aerial parts of the plant. Stem cells undergo asymmetric cell divisions to self-renew and to produce differentiating cells. Our research focused on unraveling the mechanisms governing the specification of these two distinct cell fates following the stem cell division. For this purpose, we used the model organism Physcomitrium patens, which features a singular pluripotent stem cell known as the gametophore apical cell. We show that the activity of cytokinins, critical stem cell regulators, is restricted to the gametophore apical cell due to the specific localization of PpLOG, the enzyme responsible for cytokinin activation. In turn, PpTAW, which promotes differentiating cell identity of the merophyte

SUBMITTER: Hata Y 

PROVIDER: S-EPMC11352904 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature