Investigating the Effects of Transcranial Alternating Current Stimulation on Cortical Oscillations and Network Dynamics.

ABSTRACT: Transcranial electrical brain stimulation techniques like transcranial direct current (tDCS) and transcranial alternating current (tACS) have emerged as potential tools for treating neurological diseases by modulating cortical excitability. These techniques deliver small electric currents to the brain non-invasively through electrodes on the scalp. tDCS uses constant direct current which weakly alters the membrane voltage of cortical neurons, while tACS utilizes alternating current to target and enhance cortical oscillations, though the underlying mechanisms are not fully understood more specifically. To elucidate how tACS perturbs endogenous network dynamics, we simulated spiking neuron network models. We identified distinct roles of the depolarizing and hyperpolarizing phases in driving

SUBMITTER: Agnihotri SK 

PROVIDER: S-EPMC11353238 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature