Metabolomic Approaches to Study the Potential Inhibitory Effects of Plantaricin Q7 against Listeria monocytogenes Biofilm.

ABSTRACT: Listeria monocytogenes is a serious pathogen and can exacerbate harmful effects through the formation of biofilm. Inhibition of or reduction in L. monocytogenes biofilm is a promising strategy to control L. monocytogenes in the food industry. In our previous study, it was found that plantaricin Q7 produced by Lactiplantibacillus plantarum Q7 could inhibit and reduce L. monocytogenes biofilm, but the specific mechanism remains unclear. In this study, the inhibitive and reduced activity of plantaricin Q7 on L. monocytogenes biofilm was investigated by metabolomics. The results showed that plantaricin Q7 inhibited the synthesis of L. monocytogenes biofilm mainly through purine metabolism and glycerol phospholipid metabolism, and the key differe

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11353926 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature