Pain from Internal Organs and Headache: The Challenge of Comorbidity.

ABSTRACT: Headache and visceral pain are common clinical painful conditions, which often co-exist in the same patients. Numbers relative to their co-occurrence suggest possible common pathophysiological mechanisms. The aim of the present narrative review is to describe the most frequent headache and visceral pain associations and to discuss the possible underlying mechanisms of the associations and their diagnostic and therapeutic implications based on the most recent evidence from the international literature. The conditions addressed are as follows: visceral pain from the cardiovascular, gastrointestinal, and urogenital areas and primary headache conditions such as migraine and tension-type headache. The most frequent comorbidities involve the following: cardiac ischemic pain and migraine (possibl

SUBMITTER: Affaitati G 

PROVIDER: S-EPMC11354044 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature