¹H NMR Profiling of Honey Bee Brains across Varying Ages and Seasons.

ABSTRACT: Honey bees (Apis mellifera) provide a useful model for studying aging because of the differences in longevity between the relatively short-lived summer and long-lived winter bees, as well as bees lacking signs of cognitive senescence as they age. Bee brains were dissected from newly emerged, 14-day-, and 28-day- old bees in mid- and late summer, as well as brood nest bees in fall, winter, and spring, before, during, and after overwintering, respectively. Brains were examined with nuclear magnetic resonance (NMR) spectroscopy to analyze their metabolome. Nine variable importance in projection (VIP) variables were identified, primarily amino acids and choline derivatives. Differences in metabolite concentrations were found with different ages of summer bees, mostly between newly emerg

SUBMITTER: Morfin N 

PROVIDER: S-EPMC11354335 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature