Acute Pancreatitis in Individuals with Sickle Cell Disease: A Systematic Review.

ABSTRACT: Background/Objectives: Sickle cell disease (SCD) impacts about 100,000 people in the US. SCD increases the risk of cholelithiasis and microvascular ischemia, which could increase the risk of acute pancreatitis (AP). Abdominal pain is a common presenting symptom of AP and sickle cell vaso-occlusive crisis. The purpose of our systematic review is to estimate the prevalence and determine the severity of AP in individuals with SCD compared to the general population. Methods: Multiple electronic databases were searched. We included studies that included children and adults (population) and addressed the association of SCD (exposure) with AP (outcome) compared to the same population without SCD (control). Two authors screened titles and abstracts independently, and data were abstra

SUBMITTER: Dike CR 

PROVIDER: S-EPMC11355684 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature