Prognostic Impacts of Age, Diagnosis Time, and Relapses in Primary CNS Lymphoma.

ABSTRACT: Background: The incidence of lymphomatous involvement of the central nervous system (CNS) has been increasing in recent years. However, the rarity of the disease has resulted in a scarcity of available data regarding its clinical presentation, natural history, and prognosis. We aimed to investigate the neurological characteristics of uncommon lymphomatous involvements confined to the CNS and to identify key variables that could serve as predictive biomarkers for treatment outcomes. Methods: We identified patients presenting with neurological symptoms and diagnosed with CNS-restricted lymphomatous involvement between 2005 and 2023. Results: We identified 44 cases, 93% of which were diagnosed with primary central nervous system lymphoma (PCNSL) and 7% with intravascular

SUBMITTER: Ohanyan S 

PROVIDER: S-EPMC11355736 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature