Could Flow Cytometry Provide New Prognostic Markers in Colorectal Cancer?

ABSTRACT: Background/Objectives: Colorectal cancer (CRC) is still accompanied by significant mortality, which poses the necessity of novel markers to predict treatment success and patient survival. This study aims to evaluate the prognostic and survival impact of flowytometry (FC) in CRC patients. Methods: In this prospective study, 106 surgically resectable CRC patients were included. Tissue specimens from tumor and normal mucosa were collected and analyzed by FC. DNA and tumor index were calculated. In a subgroup of 46 patients, the CD26 expression on tumor cells was estimated. These parameters were compared with patients' tumor characteristics as stage, histology data, responsiveness to treatment, metastasis/recurrence, and, finally, patients' survival to identify possible new bioma

SUBMITTER: Georvasili V 

PROVIDER: S-EPMC11355755 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature