Subjective Symptoms and Disease Activity Related to Serum Zinc Concentration in Primary Sjogren's Syndrome.

ABSTRACT: Background/Objectives: We examined the frequency of zinc deficiency in patients with Sjögren's syndrome (SS) and the relationship between zinc deficiency and each of the subjective symptoms and disease activity. Methods: We enrolled 164 patients aged ≥ 20 years with primary SS (pSS) based on the revised diagnostic criteria of the Ministry of Health, Labor and Welfare (1999) and 144 patients with RA diagnosed according to the ACR/EULAR classification criteria for RA (2010) as a comparison group. Subjective symptoms were confirmed using an original questionnaire, and disease activity was determined using the European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ESSDAI). The serum zinc concentrations were measured in both SS and RA patients. Results

SUBMITTER: Akiya K 

PROVIDER: S-EPMC11355886 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature