Drug-Related Glomerular Phenotypes: A Global Pharmacovigilance Perspective.

ABSTRACT: Introduction: Adverse drug reactions are a significant problem in modern society, stemming from the increase in prescribed medications, over-the-counter drugs, and overall polypharmacy. Glomerular disorders are one of the frequently reported renal conditions associated with medication use. VigiBase is a significant tool for evaluating events associated with drug use, and, to the authors' knowledge, no study has yet assessed this database to identify the primary medications associated with glomerular disorders. Materials and Methods: We collected data from VigiBase for 54 years and evaluated data based on global frequencies, disproportionality (IC₀₂₅ values), nephrotoxic potential, and physiopathological mechanisms. Results: Over the evaluation period, 33.932

SUBMITTER: Baptista A 

PROVIDER: S-EPMC11355908 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature