Hypermucoviscous Multidrug-Resistant <i>Klebsiella variicola</i> Strain LL2208 Isolated from Chinese Longsnout Catfish (<i>Leiocassis longirostris</i>): Highly Similar to Human <i>K. variicola</i> Strains.

ABSTRACT: Outbreaks of bacterial diseases occur in farmed Chinese longsnout catfish (Leiocassis longirostris). Due to limited information on aquatic Klebsiella variicola-infected animals, this study aimed to identify strain LL2208 isolated from diseased L. longirostris, determine its biological features, and evaluate its risk to public health. Strain LL2208 was tested for molecular identification, challenge, string, biofilm formation, and antimicrobial susceptibility. Furthermore, the whole genome of the strain was sequenced and analyzed. Based on molecular identification, strain LL2208 was identified as K. variicola. Artificial infection showed that this strain was moderately virulent to L. longirostris with an LD₅₀ = 7.92 × 10⁷ CFU/mL. Antib

SUBMITTER: Li Q 

PROVIDER: S-EPMC11356897 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature