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Wireless, battery-free, and real-time monitoring of water permeation across thin-film encapsulation.

ABSTRACT: Long-term bioelectronic implants require stable, hermetic encapsulation. Water and ion ingress are challenging to quantify, especially in miniaturized microsystems and over time. We propose a wireless and battery-free flexible platform leveraging backscatter communication and magnesium (Mg)-based microsensors. Water permeation through the encapsulation induces corrosion of the Mg resistive sensor thereby shifting the oscillation frequency of the sensing circuit. Experimental in vitro and in-tissue characterization provides information on the operation of the platform and demonstrates the robustness and accuracy of this promising method, revealing its significance for in-situ real-time monitoring of implanted bioelectronics.

SUBMITTER: Mariello M

PROVIDER: S-EPMC11358307 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Wireless, battery-free, and real-time monitoring of water permeation across thin-film encapsulation.

Mariello Massimo M Rosenthal James Daniel JD Cecchetti Francesco F Gao Mingxiang M Skrivervik Anja K AK Leterrier Yves Y Lacour Stéphanie P SP

Nature communications 20240828 1

Long-term bioelectronic implants require stable, hermetic encapsulation. Water and ion ingress are challenging to quantify, especially in miniaturized microsystems and over time. We propose a wireless and battery-free flexible platform leveraging backscatter communication and magnesium (Mg)-based microsensors. Water permeation through the encapsulation induces corrosion of the Mg resistive sensor thereby shifting the oscillation frequency of the sensing circuit. Experimental in vitro and in-tiss ...[more]

PMID: 39198382

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