Skin autofluorescence and cause-specific mortality in a population-based cohort.

ABSTRACT: We aimed to assess the association of SAF with cardiovascular mortality in the general population and the possible association between SAF with other disease-specific mortality rates. We evaluated 77,143 participants without known diabetes or cardiovascular disease. The cause of death was ascertained by the municipality database. The associations between SAF and all-cause mortality, cardiovascular mortality and cancer mortality were assessed with Cox proportional hazard analysis.After a median follow-up of 115 months, 1447 participants were deceased (1.9%). SAF and age-adjusted SAF-z score were higher in all mortality groups. Cox regression analysis revealed that the highest quartile of SAF was associated with increased odds of cardiovascular mortality, (HR) 12.6 (7.3-21.7) and after adjus

SUBMITTER: Boersma HE 

PROVIDER: S-EPMC11358541 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature