Neuroimaging of autobiographical memory in dementia with Lewy bodies: a story of insula.

ABSTRACT: Although deficits in learning and retrieving new information are well characterized in dementia with Lewy bodies, autobiographical memory has never been explored in this disease. Yet, autobiographical memory impairments are a pervasive feature of dementia, well characterized in other neurodegenerative diseases. Moreover, autobiographical memory corresponds to an extension over time of the self, which we hypothesize is altered in dementia with Lewy bodies and impairment of which could be linked to the insular atrophy occurring from an early stage of the disease. In this study, we sought to characterize autobiographical memory impairments and explore their neural correlates in dementia with Lewy bodies, on the assumption that insular damage could impact the self, including its most elaborate

SUBMITTER: Tisserand A 

PROVIDER: S-EPMC11358644 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature