Comprehensive Analysis of Drug-Induced Parkinson-like Events.

ABSTRACT: Specific drugs are well known to have the capacity to induce Parkinson-like symptoms. Parkinson-like events are side effects that may persist for an extended period even after drug administration is discontinued. Although these events can be triggered by various drugs, the mechanisms underlying their diverse symptoms remain largely unclear. To investigate this, we used the Japanese Adverse Drug Event Reporting Database, which is maintained by the Pharmaceuticals and Medical Devices Agency, to analyze the risk factors associated with Parkinson-like events along with the associated drug trends and characteristics. Our findings indicate that similar to Parkinson's disease, age-related differences affect the onset of these reported events, with older individuals being more susceptible. Hierarc

SUBMITTER: Kikegawa M 

PROVIDER: S-EPMC11359003 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature