Ultrafast Gas Chromatography-Tandem Differential Mobility Spectrometry: Toward A New Generation of On-Site, Real-Time Trace-Explosives Detection.

ABSTRACT: In the defense and security sector, rapid detection of trace quantities of threat materials is paramount. Traditional instrumentation typically relies on standalone ion mobility techniques due to being inexpensive, portable, and highly sensitive. However, these techniques face limitations when handling complex samples, suffering from low resolving power (often less than 100) and ion-suppression effects, which can lead to false-positive and false-negative results. Here, we present a foundation to the solution through the hyphenation of the flow field thermal gradient gas chromatograph (FF-TG-GC) developed by HyperChrom with a tandem differential ion mobility spectrometer (DMS-DMS) developed in-house at New Mexico State University. The FF-TG-GC demonstrates the ability to separate a variety

SUBMITTER: Threadgold JA 

PROVIDER: S-EPMC11359381 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature