A Standardized Pipeline for Assembly and Annotation of African Swine Fever Virus Genome.

ABSTRACT: Obtaining a complete good-quality sequence and annotation for the long double-stranded DNA genome of the African swine fever virus (ASFV) from next-generation sequencing (NGS) technology has proven difficult, despite the increasing availability of reference genome sequences and the increasing affordability of NGS. A gap analysis conducted by the global African swine fever research alliance (GARA) partners identified that a standardized, automatic pipeline for NGS analysis was urgently needed, particularly for new outbreak strains. Whilst there are several diagnostic and research labs worldwide that collect isolates of the ASFV from outbreaks, many do not have the capability to analyze, annotate, and format NGS data from outbreaks for submission to NCBI, and some publicly available ASFV gen

SUBMITTER: Spinard E 

PROVIDER: S-EPMC11359534 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature