Association between Low Serum Creatinine Levels and Knee Osteoarthritis in Koreans without Renal Insufficiency.

ABSTRACT:

Purpose

This study aimed to investigate the correlation between serum creatinine levels and the presence and severity of radiographic knee osteoarthritis (OA) in individuals aged ≥50 years while adjusting for potential confounders.

Materials and methods

Cross-sectional data from the 2009-2011 Korea National Health and Nutrition Examination Survey comprising 3428 individuals aged ≥50 years were utilized. The Kellgren-Lawrence (K-L) grading scale was used to assess the radiographic presence and severity of knee OA. Logistic regression and receiver operating characteristic analyses were used to investigate the association between serum creatinine levels and the presence of knee OA, whereas ordinal regression was used to assess the impact of creatinine levels on knee OA severity

SUBMITTER: Lim CW 

PROVIDER: S-EPMC11359604 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature