Comparative Genomics Revealing the Genomic Characteristics of Klebsiella variicola Clinical Isolates in China.

ABSTRACT: Klebsiella variicola is an opportunistic pathogen often misidentified as Klebsiella pneumoniae, leading to misdiagnoses and inappropriate treatment in clinical settings. The genetic and molecular characteristics of clinically isolated K. variicola remain largely unexplored. We aim to fill this knowledge gap by examining the genomic properties of and evolutionary relationships between clinical isolates of K. variicola. The genomic data of 70 K. variicola strains were analyzed using whole-genome sequencing. A phylogenetic tree was generated based on the gene sequences from these K. variicola strains and public databases. Among the K. variicola strains, the drug resistance genes with the highest carrying rates were beta-lactamase and aminoglyco

SUBMITTER: Yang F 

PROVIDER: S-EPMC11359898 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature