Updating and Refining of Economic Evaluation of Rotavirus Vaccination in Spain: A Cost-Utility and Budget Impact Analysis.

ABSTRACT: Two vaccines against rotavirus diseases, Rotarix^® and RotaTeq^®, are being marketed in Spain; but rotavirus is not presently among the diseases covered by universal vaccination in Spain. The aim of this study was to assess the efficiency of extending Spain's current targeted rotavirus vaccination strategy including only preterm babies, to a policy of universal vaccination. A de novo cohort-based Markov model was built to evaluate the efficiency of three compared rotavirus vaccination strategies in Spain: targeted, universal, and no vaccination. Using Rotarix^® or RotaTeq^®, we compared the cost-utility of these strategies from both a societal perspective and Spanish National Health System (SNHS) perspective. The model represents the most important c

SUBMITTER: Imaz-Iglesia I 

PROVIDER: S-EPMC11360725 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature