Biopolymeric Insulin Membranes for Antimicrobial, Antioxidant, and Wound Healing Applications.

ABSTRACT: Delayed wound healing increases the wound's vulnerability to possible infections, which may have lethal outcomes. The treatments available can be effective, but the urgency is not fully encompassed. The drug repositioning strategy proposes effective alternatives for enhancing medical therapies for chronic diseases. Likewise, applying wound dressings as biodegradable membranes is extremely attractive due to their ease of application, therapeutic effectiveness, and feasibility in industrial manufacturing. This article aims to demonstrate the pleiotropic effects during insulin repositioning in wound closure by employing a biopolymeric membrane-type formulation with insulin. We prepared biopolymeric membranes with sodium alginate cross-linked with calcium chloride, supported in a mixture of xa

SUBMITTER: Aguilar-Vazquez R 

PROVIDER: S-EPMC11360745 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature