Long-term outcome of kidney function in patients with ANCA-associated vasculitis.

ABSTRACT:

Background

Kidney involvement is common in anti-neutrophil cytoplasm antibody-associated vasculitis (AAV) and the prognosis is determined by the severity of kidney damage. This study focused on long-term kidney outcomes, defining possible risk factors and comparing the performance of three different histological classifications to predict outcomes for patients with AAV.

Methods

The dataset included 848 patients with newly diagnosed AAV who participated in seven randomized controlled trials (RCTs) (1995-2012). Follow-up information was obtained from questionnaires sent to the principal investigators of the original RCTs.

Results

The cumulative incidence of end-stage kidney disease (ESKD) at 5 and 10 years was 17% and 22%, respectively. Patients who developed ESKD had r

SUBMITTER: Sachez-Alamo B 

PROVIDER: S-EPMC11361807 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature