Unravelling biosynthesis and biodegradation potentials of microbial dark matters in hypersaline lakes.

ABSTRACT: Biosynthesis and biodegradation of microorganisms critically underpin the development of biotechnology, new drugs and therapies, and environmental remediation. However, most uncultured microbial species along with their metabolic capacities in extreme environments, remain obscured. Here we unravel the metabolic potential of microbial dark matters (MDMs) in four deep-inland hypersaline lakes in Xinjiang, China. Utilizing metagenomic binning, we uncovered a rich diversity of 3030 metagenome-assembled genomes (MAGs) across 82 phyla, revealing a substantial portion, 2363 MAGs, as previously unclassified at the genus level. These unknown MAGs displayed unique distribution patterns across different lakes, indicating a strong correlation with varied physicochemical conditions. Our analysis reveal

SUBMITTER: Qiu Z 

PROVIDER: S-EPMC11361885 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature