Associations of ambient air pollution and lifestyle with the risk of NAFLD: a population-based cohort study.

ABSTRACT:

Background

Both ambient air pollution and lifestyle factors contribute to the incidence of non-alcoholic fatty liver disease (NAFLD), but previous studies usually focused on single-factor associations. We aimed to assess the joint associations of ambient air pollution and lifestyle with the NAFLD risk and investigate whether lifestyle modifies the association of air pollution with NAFLD risk.

Methods

A total of 417,025 participants from the UK Biobank were included in this study. Annual average concentrations of NO₂, NO_x, PM_2.5, PM₁₀, and PM_2.5-10 were estimated. A composite lifestyle score was determined based on physical activity, alcohol intake, smoking status, dietary patterns, sedentary time, and sleep duration. Cox

SUBMITTER: Kong X 

PROVIDER: S-EPMC11363520 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature