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Risk factors for neonatal hypoglycemia: a meta-analysis.


ABSTRACT:

Objective

This Study aims to investigate the risk factors of hypoglycemia in neonates through meta-analysis.

Method

PubMed, Embase, Cochrane library, and Web of science databases were searched for case-control studies on risk factors for neonatal hypoglycemia. The search was done up to 1st October 2023 and Stata 15.0 was used for data analysis.

Results

A total of 12 published studies were included, including 991 neonates in the hypoglycemic group and 4388 neonates in the non-hypoglycemic group. Meta-analysis results suggested caesarean section [OR = 1.90 95%CI (1.23, 2.92)], small gestational age[OR = 2.88, 95%CI (1.59, 5.20)], gestational diabetes [OR = 1.65, 95%CI (1.11, 2.46)], gestational hypertension[OR = 2,79, 95%CI (1.78, 4.35)] and respiratory distress syndrome[OR = 5.33, 95%CI (2.22, 12.84)] were risk factors for neonatal hypoglycemia.

Conclusion

Based on the current study, we found that caesarean section, small gestational age, gestational diabetes, gestational hypertension, respiratory distress syndrome are risk factors for neonatal hypoglycemia.

Prospero registration number

CRD42023472974.

SUBMITTER: Wang D 

PROVIDER: S-EPMC11363588 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature

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Publications

Risk factors for neonatal hypoglycemia: a meta-analysis.

Wang Dandan D   Zhou Xuchen X   Ning Juan J   He Fen F   Shi Junhui J   Jin Xuefeng X  

BMC endocrine disorders 20240830 1


<h4>Objective</h4>This Study aims to investigate the risk factors of hypoglycemia in neonates through meta-analysis.<h4>Method</h4>PubMed, Embase, Cochrane library, and Web of science databases were searched for case-control studies on risk factors for neonatal hypoglycemia. The search was done up to 1st October 2023 and Stata 15.0 was used for data analysis.<h4>Results</h4>A total of 12 published studies were included, including 991 neonates in the hypoglycemic group and 4388 neonates in the no  ...[more]

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