Interleukin-6, -17, and -35 levels in association with clinical status in stage III and stage IV periodontitis: a cross-sectional study.

ABSTRACT:

Background

This study compared the concentrations of interleukin (IL)-6, IL-17, and IL-35 in the gingival crevicular fluid of periodontally healthy participants with individuals who had stage III and IV periodontitis.

Methods

In total, 60 participants with stage III grade B-C (n = 12)-stage IV grade C (n = 18) periodontitis and 30 healthy controls were included in this cross-sectional study. Full-mouth clinical periodontal measurements were performed. Concentrations of IL-6, IL-17, and IL-35 were determined using enzyme-linked immunosorbent assays. Parametric/nonparametric methods, Pearson's/Spearman's correlation, and logistic regression methods were used for data analyses.

Results

The periodontitis group exhibited significantly higher levels of IL-6, IL-17, and IL-3

SUBMITTER: Altaca M 

PROVIDER: S-EPMC11363592 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature