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ABSTRACT: Background
Cardiovascular disease (CVD) is a major health concern for middle-aged and older adults, with lifestyle and metabolic risk factors well-studied. However, the role of psychosocial factors in CVD remains underexplored.Objective
This study aims to delve into the connection between psychosocial factors and the occurrence of CVD.Methods
We utilized data from the UK Biobank, a large-scale study covering adults aged 38 to 73 recruited from various centers across the UK between 2006 and 2010. We employed Cox proportional hazards models to analyze the relationship between social isolation, loneliness, and incident CVD. CVD diagnoses were confirmed through hospital records and death-register data. Additionally, we conducted mediation analyses to assess the impact o
SUBMITTER: Ding L
PROVIDER: S-EPMC11363651 | biostudies-literature | 2024 Aug
REPOSITORIES: biostudies-literature