Effect of a single versus serial platelet-rich plasma injection on the healing of acute patellar tendon defect: an experimental study.

ABSTRACT:

Background

There is no consensus on the frequency and timing of platelet-rich plasma (PRP) injection in tendon healing. We aimed to evaluate the effectiveness of single versus multiple PRP injections in the healing of patellar tendon defects in the experimental model, through histological and biomechanical investigation.

Methods

Forty-four male skeletally mature Dutch rabbits were randomly divided into the five study groups ( A, B,C, D,E). After creating a longitudinal acute patellar tendon defect on both knees (One-third the width of the patella tendon), the right legs of the rabbits were used as the intervention group and the left legs as the control groups. Animals in groups A, B, and C were euthanized on days 7, 14, and 28, respectively, after the first PRP injection. An

SUBMITTER: Ghaderi MT 

PROVIDER: S-EPMC11363653 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature