Guideline-directed medical therapy prescribing patterns and in-hospital outcomes among heart failure patients during COVID-19.

ABSTRACT:

Study objective

The association of prior to admission guideline-directed medical therapy (GDMT) use in patients hospitalized with Heart Failure with Reduced Ejection Fraction (HFrEF, ejection fraction ≤40 %) and Coronavirus Disease 2019 (COVID-19) with in-hospital outcomes has not been well studied.

Design/setting/participants/interventions/outcome measures

Using the American Heart Association's Get With The Guidelines Heart Failure Registry, we identified HFrEF patients presenting with acute decompensated heart failure (ADHF) and compared rates of GDMT prescription between those presenting prior to and during the pandemic. In a subgroup of patients with a concomitant COVID-19 diagnosis, we evaluated the association of prior to admission GDMT use with in-hospital mortality a

SUBMITTER: Srivastava PK 

PROVIDER: S-EPMC11363726 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature