CBGDA: a manually curated resource for gene-disease associations based on genome-wide CRISPR.

ABSTRACT: The field of understanding the association between genes and diseases is rapidly expanding, making it challenging for researchers to keep up with the influx of new publications and genetic datasets. Fortunately, there are now several regularly updated databases available that focus on cataloging gene-disease relationships. The development of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9 system has revolutionized the field of gene editing, providing a highly efficient, accurate, and reliable method for exploring gene-disease associations. However, currently, there is no resource specifically dedicated to collecting and integrating the latest experimentally supported gene-disease association data derived from genome-wide CRISPR screening. To address this gap, we

SUBMITTER: Du Q 

PROVIDER: S-EPMC11363955 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature