<i>Akkermansia muciniphila</i>: A promising probiotic against inflammation and metabolic disorders.

ABSTRACT: Metabolic disease is a worldwide epidemic that has become a public health problem. Gut microbiota is considered to be one of the important factors that maintain human health by regulating host metabolism. As an abundant bacterium in the host gut, A. muciniphila regulates metabolic and immune functions, and protects gut health. Multiple studies have indicated that alterations in the abundance of A. muciniphila are associated with various diseases, including intestinal inflammatory diseases, obesity, type 2 diabetes mellitus, and even parasitic diseases. Beneficial effects were observed not only in live A. muciniphila, but also in pasteurized A. muciniphila, A. muciniphila-derived extracellular vesicles, outer membrane, and secreted proteins. Although numerous stu

SUBMITTER: Zhao Y 

PROVIDER: S-EPMC11364076 | biostudies-literature | 2024 Dec

REPOSITORIES: biostudies-literature