Postoperative radiotherapy for completely resected thymoma and thymic carcinoma: A systematic review and meta-analysis.

ABSTRACT:

Background

The role of postoperative radiotherapy (PORT) after complete tumor resection in patients with thymoma or thymic carcinoma remains controversial. We performed a meta-analysis to identify groups that would benefit from PORT.

Methods

Multiple scientific databases were systematically searched for studies comparing overall survival (OS) and/or disease-free survival (DFS) between PORT and surgery alone in patients with completely resected thymomas or thymic carcinomas until April 10, 2024. A random-effects model was used for the statistical analysis.

Results

A total of 31 studies with 10543 patients were included (17 studies involving 4763 patients with thymoma, seven studies involving 1045 patients with thymic carcinoma, and seven studies involving 4735 patients

SUBMITTER: He T 

PROVIDER: S-EPMC11364254 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature