Association between antibiotics use and osteoporotic fracture risk: a nationally representative retrospective cohort study.

ABSTRACT: This population-based retrospective cohort study aimed to estimate the association between antibiotic exposure and osteoporotic fracture risk. Long-term antibiotic use was associated with the risk of osteoporotic fracture. An increase in the number of antibiotic classes prescribed may also be associated with an increased osteoporotic fracture risk.

Purpose

This study aims to examine the association between antibiotic usage and osteoporotic fractures in a large cohort of Korean adults, with a specific focus on the duration of antibiotic exposure and the number of antibiotic classes used.

Methods

This retrospective cohort study from the National Health Insurance Service-National Health Screening Cohort (NHIS-HEALS) database from January 1, 2002, to December 31, 2019, included 1

SUBMITTER: Lee JW 

PROVIDER: S-EPMC11364706 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature