Influence of diabetes on microbiome in prostate tissues of patients with prostate cancer.

ABSTRACT:

Background

Although microbiota in prostatic tissues of patients with prostate cancer have been studied, results of different studies have been inconsistent. Different ethnicity of study subjects, different study designs, and potential contaminations during sample collection and experiments might have influenced microbiome results of prostatic tissues. In this study, we analyzed microbiota and their potential functions in benign and malignant tissues of prostate cancer considering possible contaminants and host variables.

Materials and methods

A total of 118 tissue samples (59 benign tissues and 59 malignant tissues) obtained by robot-assisted laparoscopic radical prostatectomy were analyzed and 64 negative controls (from sampling to sequencing processes) were included to red

SUBMITTER: Lee JJ 

PROVIDER: S-EPMC11365045 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature