Sex differences in association of healthy eating pattern with all-cause mortality and cardiovascular mortality.

ABSTRACT:

Background

Although the Healthy Eating Index (HEI) is widely recommended to reduce the risk of cardiovascular disease and all-cause death, there are significant differences in physiological and nutritional factors between the sexes. The potential impact of sex on adult dietary health is still poorly understood. The study was designed to assess whether the health benefits of diet differed by sex.

Methods

In a prospective study of 39,567 U.S. adults (51.2% female, age 46.8 ± 17.6 years), we examined sex-specific, multivariable-adjusted associations of HEI with all-cause mortality and cardiovascular disease mortality. Restricted cubic splines (RCS), subgroup analysis, propensity score matching (PSM), random forest feature importance, and sensitivity analysis were also used.

SUBMITTER: Yao H 

PROVIDER: S-EPMC11365166 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature